A few Python frameworks can be used to create APIs, two of which are Flask and Django. Frameworks comes with functionality that makes it easy for developers to implement the features that users need to interact with their applications. The complexity of a web application could be a deciding factor when you’re choosing which framework to work with. Django Django is a robust framework that has a predefined structure with built-in functionality.

https://www.smashingmagazine.com/2020/08/api-flask-google-cloudsql-app-engine/