1.15 Desperately Seeking Serena
- Do The Panic" by Phantom Planet. - SAT prep montage.
-"Campus" by Vampire Weekend. - Nate, Dan & Vanessa talk about SATs.
-"Crimewave" by Crystal Castles vs. Health. - Serena meets Georgina for drinks.
- "Elevator" by Flo Rida - Blair torments Nelly with music
- "Nice Sweet Sexy" by Difx FT. Imperio & Cru - Georgina & Serena reminisce; Serena calls Chuck for help.
- "We Started Nothing" by The Tings Tings - Georgina asks Serena about Dan, then drugs Serena's drink.
1.16 All About My Brother
-"Cheap & Cheerful" by The Kills. - Plays just before Lily run into Rufus.
- "Sonata for Violin and Piano No. 5 in F Major, Op. 24 - "Spring": I. Allegro" by Beethoven. - Rufus & Lily discuss Jenny; repeats as Lily tries on a wedding dress while chatting with Rufus.
- "Say (All I Need)" by OneRepublic. - Georgina has dinner with Serena & her family.
- "Paralyzer" by Finger Eleven.- Blair crashes Asher's party.
- "U.R.A. Fever" by The Kills. - Serena meets 'Sarah'; repeats as Serena confesses to Blair.
"- Shut Up & Let Me Go" by The Ting Tings. - The girls ask Jenny about her first time.
1.17 Woman On The Verge
- "Cities In Dust" by Junkie XL ft Lauren Rocket.- Montage of Georgina phoning Serena; repeats as Lily searches Serena's room.
- "Hook & Line" by The Kills. - Sex tape continued; repeats as Serena breaks down after her story & as Dan & Georgina kiss.
- "Fight Song" by Republic Tigers. - Serena Blair & Chuck arrive at Bart & Lily's rehearsal dinner.
- "Stay" by Lisa Loeb. Performed as Georgina tells Dan a story about an ex-boyfriend.
- "Everytime" by Lincoln Hawk. Lincoln Hawk performs as the gang arrives at the concert.
- ''Die Everyday" by Lincoln Hawk
- "True Love" by Angels and Airwaves
1x18 Much 'I Do' About Nothing
- Beautiful World" by Carolina Liar. - Serena phones Dan; repeats during Lily & Bart's wedding ceremony.
- "Do You Wanna" by The Kooks. - Blair reunites Georgina with her parents; repeats as Blair heads off to Europe without Chuck; end montage.
- "Time To Pretend" by MGMT. - Wedding prepartions & arrivals.
- "Bridal Chorus" by Wagner. - The wedding begins.
- "The Ice Is Getting Thinner" by Death Cab For Cutie. - Chuck's best man speech; Blair & Chuck kiss; Dan & Serena are forced to dance together.